Reaktion #215023

Reaktionsgleichung

morpholine

cyclohexanone

→

title compound

Cyclohexanone morpholine enamine

Lösungsmittel

hexane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis heated
2. 2
   Temperaturto reflux under nitrogen with a Dean-Stark trap for 18 hours
3. 3
   workup.DISTILLATIONThe aqueous phase (206 ml.) is collected in the distillate trap
4. 4
   workup.DISTILLATIONThe mixture is distilled under vacuum
5. 5
   Temperaturincreasing the vacuum to 29 inches and 90°-100°

Vorschrift

A mixture of morpholine (697 ml.), cyclohexanone (820 ml.) and hexane (800 ml.) is heated to reflux under nitrogen with a Dean-Stark trap for 18 hours. The aqueous phase (206 ml.) is collected in the distillate trap. The mixture is distilled under vacuum increasing the vacuum to 29 inches and 90°-100° to give the title compound as an oily residue.

Quelle