Reaktion #214997

Reaktionsgleichung

formanilide

sodium hydride

sodium

2-chloro-5-nitrobenzotrifluoride

→

4-nitrodiphenylamine

Lösungsmittel

dimethylformamide

Reaktionsbedingungen

Vorschrift

the formanilide is treated with a one-molar equivalent of sodium hydride in dimethylformamide and the resulting solution of the sodium salt is treated with 2-chloro-5-nitrobenzotrifluoride (U.S. Pat. No. 3,657,350) at an elevated temperature (e.g., 155° C., reflux), to give the 4-nitrodiphenylamine (J. Organic Chemistry, 42, 1786 (1977) and references therein).

Quelle