Reaktion #214617

Reaktionsgleichung

hydrogen

6,7-dibromo-8-nitro-1,4-benzodioxane-5-carboxylic acid

→

8-amino-1,4-benzodioxane-5-carboxylic acid

Ausbeute 83.7%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe mixture was filtered
2. 2
   workup.ADDITIONtreated with 95 ml of hydrochloric acid
3. 3
   SonstigeThe precipitate was dried off
4. 4
   Waschenwashed
5. 5
   Sonstigedried

Vorschrift

400 ml of water, 98.5 g of 6,7-dibromo-8-nitro-1,4-benzodioxane-5-carboxylic acid, 100 ml of soda and 10 g of Pd/c were introduced into an autoclave and then hydrogen under a pressure of 40 kg/cm2 was introduced while heating to 50° C. The mixture was filtered and then treated with 95 ml of hydrochloric acid. The precipitate was dried off, washed and dried. 42 g of 8-amino-1,4-benzodioxane-5-carboxylic acid were obtained (M.P.: 186° C.; yield: 83.7%).

Quelle