Reaktion #214066

Reaktionsgleichung

1-(4-chlorophenoxy)-1-(1,2,4-triazol-1-yl)-3,3-dimethyl-4-chloro-butan-2-ol

acetic anhydride

→

1-(4-chlorophenoxy)-1-(1,2,4-triazol-1-yl)-2-acetoxy-3,3-dimethyl-4-chloro-butane

Ausbeute 65.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThereafter, it was concentrated
2. 2
   workup.DISTILLATIONby distilling off excess acetic anhydride in vacuo
3. 3
   Sonstigeto crystallize out at 0° C

Vorschrift

23.1 g (0.07 mol) of 1-(4-chlorophenoxy)-1-(1,2,4-triazol-1-yl)-3,3-dimethyl-4-chloro-butan-2-ol were dissolved in 100 ml of acetic anhydride and the solution was heated to 100° C. for 12 hours. Thereafter, it was concentrated by distilling off excess acetic anhydride in vacuo. The oil which remained was taken up in 150 ml of diisopropyl ether and the product was allowed to crystallize out at 0° C. 17 g (65% of theory) of 1-(4-chlorophenoxy)-1-(1,2,4-triazol-1-yl)-2-acetoxy-3,3-dimethyl-4-chloro-butane of melting point 111°-117° were obtained.

Quelle