Reaktion #2139441

ord-91bc3a7871d04c03a455bffc3b94b6e6

Reaktionsgleichung

Cc1ccccc1CS
2-methylbenzylmercaptan
C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@@H]2OS(C)(=O)=O
17β-methanesulfonyloxy-1,4-androstadiene-3,11-dione
→
Cc1ccccc1CS[C@@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3C(=O)C[C@]12C
title compound
Cc1ccccc1CS[C@@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3C(=O)C[C@]12C
17α-(2'-Methylbenzylthio)-1,4-Androstadiene-3,11-Dione

Edukte

Cc1ccccc1CS
2-methylbenzylmercaptan
C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@@H]2OS(C)(=O)=O
17β-methanesulfonyloxy-1,4-androstadiene-3,11-dione

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

In a manner similar to that described in Example 1A, 2-methylbenzylmercaptan is reacted with 17β-methanesulfonyloxy-1,4-androstadiene-3,11-dione to obtain the title compound of this example.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04183924uspto-grants-1980_01