Reaktion #2138651

Reaktionsgleichung

1-chloro-4-(4-nitrophenyl)-2-oxo-3-butene

hydrazinecarbothioic acid O-methylester

→

5-[2-(4-nitrophenyl)ethenyl]-5,6-dihydro-1,3,4-thiadiazin2(3H)one

Lösungsmittel

acetonitrile

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for 3 h
2. 2
   FiltrationThe crystals were filtered
3. 3
   Waschenwashed with acetonitrile and ether

Vorschrift

A solution containing 11.2 g of 1-chloro-4-(4-nitrophenyl)-2-oxo-3-butene (J. Org. Chem. 28, 2446, 1963) and 6.8 g of hydrazinecarbothioic acid O-methylester in 200 ml of acetonitrile was refluxed for 3 h. The crystals were filtered and washed with acetonitrile and ether. Yield 7.7 g (59%), mp. 231°-240° C.

Quelle