Reaktion #2137712

Reaktionsgleichung

sodium methoxide

sodium

S-(3,4-dihydroxyphenyl)-isothiourea

2-methylbutyl tosylate

→

4-(2-methylbutylthio)-catechol

Lösungsmittel

methanol

methanol

methanol

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeequipped with a magnetic stirrer and under a nitrogen flow
2. 2
   TemperaturThe solution was heated

Vorschrift

22 g (0.1 mole) of S-(3,4-dihydroxyphenyl)-isothiourea were dissolved in 50 ml of anhydrous methanol in a 1 litre flask equipped with a magnetic stirrer and under a nitrogen flow. The solution was heated and a solution of sodium methoxide containing 9.2 g of sodium (4 equivalents) in 150 ml of anhydrous methanol was added. 24.2 g (0.1 mole) of 2-methylbutyl tosylate in solution in 50 ml of methanol were poured into the reaction mixture at the boiling point of methanol.

Quelle