Reaktion #2137

ord-7aefd98413d44b3fac3a2bd4ea211f8d

Reaktionsgleichung

CCCn1cnc2c1c(=O)[nH]c(=O)n2C
3-methyl-7-propyl-xanthine
CCOP(=O)(CCCBr)OCC
diethyl 3-bromopropanephosphonate
→
CCCn1cnc2c1c(=O)n(CCCP(=O)(OCC)OCC)c(=O)n2C
Diethyl [3-(3-methyl-7-propylxanthin-1-yl)propyl]phosphonate

Edukte

CCCn1cnc2c1c(=O)[nH]c(=O)n2C
3-methyl-7-propyl-xanthine
CCOP(=O)(CCCBr)OCC
diethyl 3-bromopropanephosphonate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title substance was prepared from 0.048 mol of 3-methyl-7-propyl-xanthine and 0.058 mol of diethyl 3-bromopropanephosphonate analogously to Example 23.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05728686uspto-grants-1998_03