Reaktion #2131

ord-8db1122947c440319b376bdd83c6820e

Reaktionsgleichung

Cn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccccc1
7-benzyl-3-methylxanthine
CCOP(=O)(CCCBr)OCC
diethyl 3-bromopropanphosphonate
→
CCOP(=O)(CCCn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O)OCC
Diethyl [7-benzyl-3-(3-methylxanthin-1-yl)propyl]phosphonate

Edukte

Cn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccccc1
7-benzyl-3-methylxanthine
CCOP(=O)(CCCBr)OCC
diethyl 3-bromopropanphosphonate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title substance was prepared from 7-benzyl-3-methylxanthine, (0.04 mol) and diethyl 3-bromopropanphosphonate (0.046 mol) analogously to Example 23.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05728686uspto-grants-1998_03