Reaktion #2122

ord-38aa921c2f824a8a8df4283d74a543c9

Reaktionsgleichung

Cn1cnc2c1c(=O)[nH]c(=O)n2C
theobromine
CCOP(=O)(CCCBr)OCC
diethyl 3-bromopropanephosphonate
→
CCOP(=O)(CCCn1c(=O)c2c(ncn2C)n(C)c1=O)OCC
Diethyl [3-(3,7-dimethylxanthin-1-yl)propyl]phosphonate

Edukte

Cn1cnc2c1c(=O)[nH]c(=O)n2C
theobromine
CCOP(=O)(CCCBr)OCC
diethyl 3-bromopropanephosphonate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title substance was prepared from 0.067 mol of theobromine and 0.08 mol of diethyl 3-bromopropanephosphonate analogously to Example 32.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05728686uspto-grants-1998_03