Reaktion #2103

Reaktionsgleichung

7-ethoxymethylxanthine

1,5-dibromopentane

potassium carbonate

→

1-(5-Bromopentyl)-7-ethoxymethyl-3-methylxanthine

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe solution was filtered
2. 2
   Einengenconcentrated
3. 3
   Sonstigethe oily residue which remained was chromatographed (eluent: ethyl acetate)

Vorschrift

22.4 g (0.1 mol) of 7-ethoxymethylxanthine were stirred at 70° C. for 1.5 hours with 45.9 g (0.2 mol) of 1,5-dibromopentane and 27.6 g of activated potassium carbonate. The solution was filtered and concentrated, and the oily residue which remained was chromatographed (eluent: ethyl acetate).

Quelle