Reaktion #2102589

ord-8c50093cdc4c4735bd890e119d2cbffa

Reaktionsgleichung

O=C(Cc1ccccn1)Nc1ccc(Br)nn1
O=C(Cc1ccccn1)Nc1ccc
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C
CC1(C)OB(C2=CC(=O)CC
→
O=C1C=C(c2ccc(NC(=O)Cc3ccccn3)nn2)CC1
O=C1C=C(c2ccc(NC(=O)

Edukte

O=C(Cc1ccccn1)Nc1ccc(Br)nn1
O=C(Cc1ccccn1)Nc1ccc(Br)nn1
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C

Reagenzien

[Na+].[OH-]
NaOH
O
water
c1ccc(-c2c3ccccc3cc3ccccc23)cc1
9-Phenylanthracene
CC(C)(C)P(C1CCCC1)C(C)(C)C.CC(C)(C)P(C1CCCC1)C(C)(C)C.[Cl][Pd][Cl].[Fe]
Pd(dtbpf)Cl2

Lösungsmittel

CO
MeOH

Reaktionsbedingungen

Temperatur
80°CELSIUS

Quelle

DOI: 10.1038/s4155739k HTE dataset from Pfizer