Reaktion #2102585

ord-af1880d1d1404919b7d24785a5dde644

Reaktionsgleichung

O=C(Cc1ccccn1)Nc1ccc(Br)nn1
O=C(Cc1ccccn1)Nc1ccc
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C
CC1(C)OB(C2=CC(=O)CC
→
O=C1C=C(c2ccc(NC(=O)Cc3ccccn3)nn2)CC1
O=C1C=C(c2ccc(NC(=O)

Edukte

O=C(Cc1ccccn1)Nc1ccc(Br)nn1
O=C(Cc1ccccn1)Nc1ccc(Br)nn1
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C

Reagenzien

O=P([O-])([O-])[O-].[K+].[K+].[K+]
K3PO4
O
water
c1ccc(-c2c3ccccc3cc3ccccc23)cc1
9-Phenylanthracene
—
3G OMs tBuBrettPhos

Lösungsmittel

C1CCOC1
THF

Reaktionsbedingungen

Temperatur
80°CELSIUS

Quelle

DOI: 10.1038/s4155739k HTE dataset from Pfizer