Reaktion #2102583

ord-1bb1de95503941629909a1c870025729

Reaktionsgleichung

O=C(Cc1ccccn1)Nc1ccc(Br)nn1
O=C(Cc1ccccn1)Nc1ccc
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C
CC1(C)OB(C2=CC(=O)CC
→
O=C1C=C(c2ccc(NC(=O)Cc3ccccn3)nn2)CC1
O=C1C=C(c2ccc(NC(=O)

Edukte

O=C(Cc1ccccn1)Nc1ccc(Br)nn1
O=C(Cc1ccccn1)Nc1ccc(Br)nn1
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C

Reagenzien

O=C([O-])O.[Na+]
NaHCO3
O
water
c1ccc(-c2c3ccccc3cc3ccccc23)cc1
9-Phenylanthracene
CN(C)c1ccc(P(C(C)(C)C)C(C)(C)C)cc1.CN(C)c1ccc(P(C(C)(C)C)C(C)(C)C)cc1.[Cl][Pd][Cl]
Pd-132

Lösungsmittel

CO
MeOH

Reaktionsbedingungen

Temperatur
80°CELSIUS

Quelle

DOI: 10.1038/s4155739k HTE dataset from Pfizer