Reaktion #2102579

ord-35f032b5147a48a7914c560c20e087eb

Reaktionsgleichung

O=C(Cc1ccccn1)Nc1ccc(Br)nn1
O=C(Cc1ccccn1)Nc1ccc
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C
CC1(C)OB(C2=CC(=O)CC
→
O=C1C=C(c2ccc(NC(=O)Cc3ccccn3)nn2)CC1
O=C1C=C(c2ccc(NC(=O)

Edukte

O=C(Cc1ccccn1)Nc1ccc(Br)nn1
O=C(Cc1ccccn1)Nc1ccc(Br)nn1
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C
CC1(C)OB(C2=CC(=O)CC2)OC1(C)C

Reagenzien

[Cs+].[F-]
CsF
c1ccc(-c2c3ccccc3cc3ccccc23)cc1
9-Phenylanthracene
ClCCl.[Cl][Pd][Cl].[Fe].c1ccc(P(c2ccccc2)C2CCCC2)cc1.c1ccc(P(c2ccccc2)C2CCCC2)cc1
Pd(dppf)2Cl2

Lösungsmittel

CO
MeOH

Reaktionsbedingungen

Temperatur
80°CELSIUS

Quelle

DOI: 10.1038/s4155739k HTE dataset from Pfizer