Reaktion #2097

ord-37d510efe3de46df8fb8264294561f22

Reaktionsgleichung

CCCn1c(=O)c2[nH]cnc2n(CCC)c1=O
1,3-dipropylxanthine
CCOP(=O)(CCCBr)OCC
diethyl 3-bromopropanephosphonate
→
CCCn1c(=O)c2c(ncn2CCCP(=O)(OCC)OCC)n(CCC)c1=O
Diethyl [3-(1,3-dipropylxanthin-7-yl)propyl]phosphonate

Edukte

CCCn1c(=O)c2[nH]cnc2n(CCC)c1=O
1,3-dipropylxanthine
CCOP(=O)(CCCBr)OCC
diethyl 3-bromopropanephosphonate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigechromatographed on silica gel (eluent: ethyl acetate/methanol 20:1)

Vorschrift

The title substance was prepared from 1,3-dipropylxanthine and diethyl 3-bromopropanephosphonate analogously to Example 1 and chromatographed on silica gel (eluent: ethyl acetate/methanol 20:1).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05728686uspto-grants-1998_03