Reaktion #2093

Reaktionsgleichung

7-benzyl-1-ethoxymethyl-3-methylxanthine

→

1-Ethoxymethyl-3-methylxanthine

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe catalyst was filtered off
2. 2
   Einengenthe filtrate was concentrated to dryness
3. 3
   Sonstigecrystallized from dimethylformamide/diisopropyl ether

Vorschrift

17.5 g (0.056 mol) of 7-benzyl-1-ethoxymethyl-3-methylxanthine were hydrogenated over 1.8 g of palladium (10%) on activated carbon at room temperature for 8 hours in 500 ml of ethanol. The catalyst was filtered off and the filtrate was concentrated to dryness and crystallized from dimethylformamide/diisopropyl ether.

Quelle