Reaktion #2088462

ord-2f37d3d7516f432fbdaea32f3fd04528

Reaktionsgleichung

O=CN1C(=O)c2ccccc2S1(=O)=O
O=CN1C(=O)c2ccccc2S1
CC(C)(C)OC(=O)N1CCc2cc(Br)cc(OCc3ccccc3)c2C1
CC(C)(C)OC(=O)N1CCc2
CC[Si](CC)CC
CC[Si](CC)CC
→
CC(C)(C)OC(=O)N1CCc2cc(C=O)cc(OCc3ccccc3)c2C1
CC(C)(C)OC(=O)N1CCc2

Edukte

O=CN1C(=O)c2ccccc2S1(=O)=O
O=CN1C(=O)c2ccccc2S1(=O)=O
CC(C)(C)OC(=O)N1CCc2cc(Br)cc(OCc3ccccc3)c2C1
CC(C)(C)OC(=O)N1CCc2cc(Br)cc(O
CC[Si](CC)CC
CC[Si](CC)CC

Reagenzien

CC(=O)[O][Pd][O]C(C)=O
Pd(OAc)2
c1ccc(-c2c3ccccc3cc3ccccc23)cc1
9-Phenylanthracene
CCN(C(C)C)C(C)C
DIPEA
CC1(C)O[C@H](CP(c2ccccc2)c2ccccc2)[C@@H](CP(c2ccccc2)c2ccccc2)O1
(S,S)-DIOP

Lösungsmittel

CN(C)C=O
DMF

Reaktionsbedingungen

Temperatur
80°CELSIUS

Quelle

DOI: 10.1038/s4155739k HTE dataset from Pfizer