Reaktion #2085

Reaktionsgleichung

1-benzyl-7-ethoxymethyl-3-methylxanthine

hydrochloric acid

→

desired product

1-Benzyl-3-methylxanthine hydrochloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe precipitated solid was filtered off with suction
2. 2
   Waschenwashed with ethanol
3. 3
   Sonstigedried under reduced pressure (164 g)
4. 4
   Einengenafter concentrating to approximately 50%

Vorschrift

The unpurified 1-benzyl-7-ethoxymethyl-3-methylxanthine was treated with 1000 ml of 5N hydrochloric acid and stirred at 60° C. for 6 hours. The precipitated solid was filtered off with suction, washed with ethanol and dried under reduced pressure (164 g). It was possible from the mother liquor, after concentrating to approximately 50%, to isolate a further 35 g of the desired product.

Quelle