Reaktion #2080180

Reaktionsgleichung

2-methyl-4,4-bis(methyloxy)-3-[4-(methyloxy)phenyl]-2-cyclobuten-1-one

2-Methyl-4,4-bis(methyloxy)-3-[4-(methyloxy)phenyl]-2-cyclobuten-1-one

4-methoxyphenylmagnesium bromide

→

4-Hydroxy-3-methyl-2,4-bis[4-(methyloxy)phenyl]-2-cyclobuten-1-one

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeSynthesized

Vorschrift

Synthesized according to the procedure utilized for Example 46 (Step 2) using 2-methyl-4,4-bis(methyloxy)-3-[4-(methyloxy)phenyl]-2-cyclobuten-1-one (260) and 4-methoxyphenylmagnesium bromide. 1H NMR (CDCl3, 300 MHz) δ 7.39-7.29 (m, 4H), 7.10-6.88 (m, 4H), 3.88 (s, 3H), 3.85 (s, 3H), 2.47 (s, 3H). TLC (60:40; hexanes/EtOAc): Rf=0.23.

Quelle