Reaktion #2075746

Reaktionsgleichung

quinoline

2-carbomethoxy-4-hydroxy-8-methylthioquinoline

2-methylmercaptoaniline

quinoline

→

2-carbomethoxy-4-hydroxy-8-methylquinoline

Ausbeute 59.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewas obtained (1.24 g, 59% yield over two steps)

Vorschrift

Employing the same sequence as employed in the preparation of quinoline F3 but starting with the commercially available o-toluidene (Aldrich Chemical Co.) rather than 2-methylmercaptoaniline (F1) the desired quinoline I1 was obtained (1.24 g, 59% yield over two steps).

Quelle