Reaktion #2069924

Reaktionsgleichung

Acetic anhydride

4-isopropylaniline

→

N-Acetyl-4-isopropylaniline

Lösungsmittel

chloroform

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturIn the course of this, intense heating of the reaction mixture
2. 2
   workup.ADDITIONOn completion of the dropwise addition
3. 3
   EinengenThe reaction mixture is concentrated to dryness
4. 4
   Sonstigethe resulting, reddish-white solid is recrystallized from hexane

Vorschrift

Acetic anhydride (26.0 g, 254 mmol) is slowly added dropwise to a solution of 4-isopropylaniline (17.2 g, 127 mmol) in 80 ml of chloroform. In the course of this, intense heating of the reaction mixture occurs. On completion of the dropwise addition, the mixture is stirred at room temperature for another 2 h. The reaction mixture is concentrated to dryness and the resulting, reddish-white solid is recrystallized from hexane.

Quelle