Reaktion #2063910

ord-c0cbc8e151a94462909b62abb3079da1

Reaktionsgleichung

Cn1cc(C(=O)C(=O)Cl)c2ccc(F)cc21
(6-Fluoro-1-methyl-1H-indol-3-yl)-oxo-acetyl chloride
CC(C)OC(=N)Cc1cn(C)c2c([N+](=O)[O-])cccc12.Cl
2-(1-methyl-7-nitro-1H-indol-3-yl)-acetimidic acid isopropyl ester hydrochloride
→
Cn1cc(C2=C(c3cn(C)c4c([N+](=O)[O-])cccc34)C(=O)NC2=O)c2ccc(F)cc21
3-(6-Fluoro-1-methyl-1H-indol-3-yl)-4-(1-methyl-7-nitro-1H-indol-3-yl)-pyrrole-2,5-dione

Edukte

Cn1cc(C(=O)C(=O)Cl)c2ccc(F)cc21
(6-Fluoro-1-methyl-1H-indol-3-yl)-oxo-acetyl chloride
CC(C)OC(=N)Cc1cn(C)c2c([N+](=O)[O-])cccc12.Cl
2-(1-methyl-7-nitro-1H-indol-3-yl)-acetimidic acid isopropyl ester hydrochloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

3-(6-Fluoro-1-methyl-1H-indol-3-yl)-4-(1-methyl-7-nitro-1H-indol-3-yl)-pyrrole-2,5-dione was prepared from (6-Fluoro-1-methyl-1H-indol-3-yl)-oxo-acetyl chloride and 2-(1-methyl-7-nitro-1H-indol-3-yl)-acetimidic acid isopropyl ester hydrochloride.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06228877B1uspto-grants-2001_05