Reaktion #2061939

Reaktionsgleichung

Pyridinium dichromate

2-(4-fluorophenylthio)-6-fluorobenzyl alcohol

→

subtitle compound

2-(4-fluorophenylthio)-6-fluorobenzaldehyde

Lösungsmittel

methylene chloride

methylene chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe reaction mixture is filtered through diatomaceous earth (Celite®)

Vorschrift

Pyridinium dichromate (8.34 g, 22.2 mmol) is suspended in 30 ml of methylene chloride. A solution of 2-(4-fluorophenylthio)-6-fluorobenzyl alcohol (3.73 g, 14.8 mmol) in 10 ml of methylene chloride is then added dropwise to the suspension. The reaction mixture is then stirred overnight. The reaction mixture is filtered through diatomaceous earth (Celite®) and then through silica gel to afford the subtitle compound. m.p. 94°-97° C.

Quelle