Reaktion #2061937

Reaktionsgleichung

2-[2-(4-fluorophenylthio)-6-fluorophenyl]-4,4-dimethyloxazoline

water

HCl

→

subtitle compound

2-(4-fluorophenylthio)-6-fluorobenzoic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis refluxed overnight
2. 2
   SonstigeThe cooled reaction mixture
3. 3
   Extraktionis extracted twice with ethyl acetate
4. 4
   WaschenThe extracts are washed with water
5. 5
   Trocknenbrine and dried over MgSO4

Vorschrift

The compound 2-[2-(4-fluorophenylthio)-6-fluorophenyl]-4,4-dimethyloxazoline (5.0 g, 15.66 mmol) is added to 310 ml of a 4.5N HCl solution in water and is refluxed overnight. The cooled reaction mixture is extracted twice with ethyl acetate. The extracts are washed with water and then brine and dried over MgSO4 to afford the subtitle compound.

Quelle