Reaktion #2045028

Reaktionsgleichung

methyl(4-nitrophenoxy)acetate

Methyl(4-Nitro phenoxy)acetate

→

40

Ausbeute 92.1%

(4-Nitro phenoxy)acetic acid

Ausbeute 92.1%

Lösungsmittel

HCl

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for 8 hours
2. 2
   FiltrationCrude 40 was filtered
3. 3
   Sonstigedried
4. 4
   Sonstigerecrystallised from a mixture of ethyl acetate:hexane (1:5)

Vorschrift

A mixture of methyl(4-nitrophenoxy)acetate 31 (100 g, 474 mmol) and concentrated HCl (1000 ml) was refluxed for 8 hours. The reaction mass was cooled to room temp. Crude 40 was filtered, dried and recrystallised from a mixture of ethyl acetate:hexane (1:5) to give pure 40 (86 g, 92.1%) as a white shining powder. M.p: 186-188.5° C.

Quelle