Reaktion #2044066

Reaktionsgleichung

N-{1-[4-(cyanomethyl)phenyl]-1-methylethyl}acrylamide

imidazole

benzyltrimethylammonium hydroxide

→

N-{1-[4-(cyanomethyl)phenyl]-1-methylethyl}-3-(imidazol-1-yl)propionamide

Lösungsmittel

1,4-dioxane

Reaktionsbedingungen

Vorschrift

A mixture of N-{1-[4-(cyanomethyl)phenyl]-1-methylethyl}acrylamide (20.5 g), imidazole (6.11 g), benzyltrimethylammonium hydroxide (74 mg) and 1,4-dioxane (300 ml) gave N-{1-[4-(cyanomethyl)phenyl]-1-methylethyl}-3-(imidazol-1-yl)propionamide as an oil.

Quelle