Reaktion #2042471

Reaktionsgleichung

LiAlH4

3-phenyl-1-indanone

→

1-phenylindene

Ausbeute 50.0%

Lösungsmittel

THF

ethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeat -5° C.
2. 2
   SonstigeThe oil obtained
3. 3
   Sonstigeby evaporating ether (40 g)
4. 4
   workup.DISSOLUTIONis dissolved in 300 ml of toluene containing 20 g of Sio2
5. 5
   Temperaturkept refluxing for 2 hours, with formed water being
6. 6
   workup.DISTILLATIONdistilled off
7. 7
   FiltrationThe resulting mixture is filtered
8. 8
   Sonstigethe solvent is evaporated and by distillation 18 g

Vorschrift

Keeping the temperature at -5° C., to a suspension of 5.0 g (0.131 moles) of LiAlH4 in 300 ml of ethyl ether, 35 g (0.168 moles) is added of 3-phenyl-1-indanone dissolved in 50 ml of THF. The oil obtained by evaporating ether (40 g), is dissolved in 300 ml of toluene containing 20 g of Sio2 and kept refluxing for 2 hours, with formed water being distilled off. The resulting mixture is filtered, the solvent is evaporated and by distillation 18 g is obtained (yield of 50%) of 1-phenylindene boiling at 95-100° C./0.2 mm Hg.

Quelle