Reaktion #2039980

ord-7b324c9ed78d45fcb253c8dfd9eb5a22

Reaktionsgleichung

Cl
Hydrochloric acid
CCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(C)C
N-decyl-[2-[[N-[3-(dimethylamino)propyl]carbamoyloxy]methyl]phenyl]formamide
→
CCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(C)C.Cl
aimed compound
CCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(C)C.Cl
N-Decyl-[2-[[N-[3-(dimethylamino)propyl]carbamoyloxy]methyl]phenyl]formamide hydrochloride

Edukte

Cl
Hydrochloric acid
CCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(C)C
N-decyl-[2-[[N-[3-(dimethylamino)propyl]carbamoyloxy]methyl]phenyl]formamide

Reagenzien

Keine

Lösungsmittel

CCOC(C)=O
ethyl acetate
CCOC(C)=O
ethyl acetate

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Einengenthe reaction mixture was concentrated

Vorschrift

4N Hydrochloric acid--ethyl acetate solution (0.14 ml) was added to a solution of N-decyl-[2-[[N-[3-(dimethylamino)propyl]carbamoyloxy]methyl]phenyl]formamide (0.200 g) in ethyl acetate (2 ml) at room temperature. After being stirred for 10 minutes, the reaction mixture was concentrated, thereby yielding 0.209 g of the aimed compound as white syrup.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06114325uspto-grants-2000_09