Reaktion #2039979

ord-af4efa3d179b4c3f800f6a6e5e1ed9f4

Reaktionsgleichung

Cl
Hydrochloric acid
CCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(C)C
[2-[[N-[3-(dimethylamino)propyl]carbamoyloxy]methyl]phenyl]-N-dodecylformamide
→
CCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(C)C.Cl
aimed compound
CCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(C)C.Cl
[2-[[N-[3-(Dimethylarnino)propyl]carbamoyloxy]methyl]phenyl]-N-dodecylformamide hydrochloride

Edukte

Cl
Hydrochloric acid
CCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(C)C
[2-[[N-[3-(dimethylamino)propyl]carbamoyloxy]methyl]phenyl]-N-dodecylformamide

Reagenzien

Keine

Lösungsmittel

CCOC(C)=O
ethyl acetate
CCOC(C)=O
ethyl acetate

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Einengenthe reaction mixture was concentrated

Vorschrift

4N Hydrochloric acid--ethyl acetate solution (0.13 ml) was added to a solution of [2-[[N-[3-(dimethylamino)propyl]carbamoyloxy]methyl]phenyl]-N-dodecylformamide (0.200 g) in ethyl acetate (2 ml) at room temperature. After being stirred for 15 minutes, the reaction mixture was concentrated, thereby yielding 0.217 g of the aimed compound as white solid.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06114325uspto-grants-2000_09