Reaktion #2025256

ord-4bb59b9f45f3412b902680b6c73b5ba0

Reaktionsgleichung

CC1(C)OB(c2cnc3ccccc3c2)OC1(C)C
CC1(C)OB(c2cnc3ccccc
Clc1ccc2cc[nH]c2c1
Clc1ccc2cc[nH]c2c1
→
c1ccc2ncc(-c3ccc4cc[nH]c4c3)cc2c1
c1ccc2ncc(-c3ccc4cc[
Ausbeute 98.0%

Edukte

CC1(C)OB(c2cnc3ccccc3c2)OC1(C)C
CC1(C)OB(c2cnc3ccccc3c2)OC1(C)
Clc1ccc2cc[nH]c2c1
Clc1ccc2cc[nH]c2c1

Reagenzien

CC(C)(C)c1ccc(-c2ccc(C(C)(C)C)cc2)cc1
CC(C)(C)c1ccc(-c2ccc(C(C)(C)C)
CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1.Nc1ccccc1-c1[c-]cccc1.[Cl][Pd+]
CC(C)c1cc(C(C)C)c(-c2ccccc2P(C
O=P([O-])([O-])[O-].[K+].[K+].[K+]
O=P([O-])([O-])[O-].[K+].[K+].

Lösungsmittel

C1CCOC1
C1CCOC1
C1CCOC1
C1CCOC1
O
water

Reaktionsbedingungen

Temperatur
100°CELSIUS

Aufarbeitung

  1. 1
    workup.STIRRING

Quelle

DOI: 10.1039/c5sc04751jPd_CN_Coupling_Informer_Library