Reaktion #2021839

ord-8d06bd17e3e846aeb4b6862159c45256

Reaktionsgleichung

O=C(NCc1ccc2c(c1)OCO2)c1cc([N+](=O)[O-])ccc1F
2-fluoro-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide
CCCCC(N)CO
2-amino-1-hexanol
CCCCC(CO)Nc1ccc([N+](=O)[O-])cc1C(=O)NCc1ccc2c(c1)OCO2
2-[1-(1-Hydroxymethyl)pentylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide
Ausbeute 77.8%

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2-[1-(1-Hydroxymethyl)pentylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide (203 mg) was prepared from 2-fluoro-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide (200 mg) and 2-amino-1-hexanol (221 mg) in a similar manner to that of Example 1(1) as yellow crystals. mp 112-115° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06384080B1uspto-grants-2002_05