Reaktion #2015309

Reaktionsgleichung

2-(3-bromo-phenyl)-4-(3,4-dichloro-phenyl)-6-methyl-pyrimidine

2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

→

title compound

5-{3-[4-(3,4-Dichloro-phenyl)-6-methyl-pyrimidin-2-yl]-phenyl}-pyridin-2-ylamine

Reaktionsbedingungen

Vorschrift

The title compound was prepared from 2-(3-bromo-phenyl)-4-(3,4-dichloro-phenyl)-6-methyl-pyrimidine (example E.62) (0.2 g, 0.5 mmol) and commercially available 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (0.14 g, 0.65 mmol) according to the general procedure VI. Obtained as an off-white solid (0.11 g, 54%). MS (ISP) 407.4 [(M+H)+]; mp 170.5° C.

Quelle