Reaktion #2008591

ord-69394316c39c43308fd8f35ded3e2d3c

Reaktionsgleichung

CCc1cc(-c2ccc(S(=O)(=O)Cl)s2)c(C)[nH]c1=O
5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride
CN1CCCNCC1
1-methyl-1,4-diazepane
→
CCc1cc(-c2ccc(S(=O)(=O)N3CCCN(C)CC3)s2)c(C)[nH]c1=O.Cl
title compound
CCc1cc(-c2ccc(S(=O)(=O)N3CCCN(C)CC3)s2)c(C)[nH]c1=O.Cl
3-Ethyl-6-methyl-5-[5-(4-methyl-1,4-diazepane-1-sulfonyl)thiophen-2-yl]-1H-pyridin-2-one hydrochloride

Edukte

CCc1cc(-c2ccc(S(=O)(=O)Cl)s2)c(C)[nH]c1=O
5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride
CN1CCCNCC1
1-methyl-1,4-diazepane

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with 1-methyl-1,4-diazepane as described in Steps 5 and 6, Example 1 to give the title compound. MS: m/e 396 (M+H)

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08173682B2uspto-grants-2012_05