Reaktion #2000679

Reaktionsgleichung

hydrochloric acid

2-(di(methylthio))methylidenemalononitrile

cyanothioacetamide

triethylamine

→

product

2-Amino-6-mercapto-4-(methylthio)pyridine-3,5-dicarbonitrile

Lösungsmittel

DMF

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe resulting precipitate was filtered off with suction
2. 2
   Waschenwashed with water
3. 3
   Sonstigedried

Vorschrift

10 g (58.74 mmol) of 2-(di(methylthio))methylidenemalononitrile and 7.1 g (70.48 mmol) of cyanothioacetamide were initially charged in 21 ml of DMF, and 16.4 ml (117.47 mmol) of triethylamine were added dropwise at room temperature. The mixture was stirred at room temperature for 8 h. The reaction mixture was added to 300 ml of 3N hydrochloric acid. The resulting precipitate was filtered off with suction, washed with water and dried. This gave the product as a powder.

Quelle