Reaktion #1999205

ord-25b0846b94fa4278b078a1b60104ced3

Reaktionsgleichung

CCCCOP(=O)(CC)CCCN
butyl ethyl(3-aminopropyl)phosphinate
OCCO
ethylene glycol
→
CCP(=O)(CCCN)OCCO
2-hydroxyethyl ethyl(3-aminopropyl)phosphinate
Ausbeute 96.0%

Edukte

CCCCOP(=O)(CC)CCCN
butyl ethyl(3-aminopropyl)phosphinate
OCCO
ethylene glycol

Reagenzien

O.O=C([O-])C(=O)O.O=C([O-])C(=O)O.[K+].[K+].[O]=[Ti]
potassium titanyl oxalate

Reaktionsbedingungen

Temperatur
200°CELSIUS
Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    workup.DISTILLATIONVolatiles are distilled off
  2. 2
    Sonstigeby gradual evacuating

Vorschrift

To 414 g (2 mol) of butyl ethyl(3-aminopropyl)phosphinate (produced as in Example 6) are added 155 g (2.5 mol) of ethylene glycol and 0.4 g of potassium titanyl oxalate followed by stirring at 200° C. for 2 h. Volatiles are distilled off by gradual evacuating to leave 374 g (96% of theory) of 2-hydroxyethyl ethyl(3-aminopropyl)phosphinate.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08604232B2uspto-grants-2013_12