Reaktion #1981897

Reaktionsgleichung

hydrogen chloride

tert-butyl[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamate

→

title compound

1-(5-methyl-1,3,4-thiadiazol-2-yl)methanamine hydrochloride

Lösungsmittel

1,4-dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenthe reaction mixture was concentrated

Vorschrift

Upon cooling in an ice-water bath, to a 6 mL 4M hydrogen chloride solution in 1,4-dioxane was added the tert-butyl[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]carbamate (391 mg, 1.71 mmol). After the stirring for 1 hr, the reaction mixture was concentrated to give the title compound as white solid (351 mg).

Quelle