Reaktion #1977965

Reaktionsgleichung

solution

Ethyl 2-(2,4-difluorophenyl)acetimidate hydrochloride

cyanamide

→

titled compound

Ethyl N-cyano-2-(2,4-difluorophenyl)acetimidate

Lösungsmittel

ethanol

diethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe reaction mixture was then filtered
2. 2
   Einengenthe filtrate was concentrated

Vorschrift

To a solution of Example 4A (7.0 g, 29.7 mmol) in ethanol (100 mL) was added a solution of cyanamide (1.25 g, 29.7 mmol) in diethyl ether (25 mL). The reaction mixture was stirred at room temperature for 3 days. The reaction mixture was then filtered and the filtrate was concentrated to obtain the titled compound. MS (ESI+) m/z 225 (M+H)+.

Quelle