Reaktion #1973928

ord-2c5e79c602a84d9fa0caec80d5c30337

Reaktionsgleichung

CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
5c
CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
2-(12-phthalimido dodecyl)propane dioic acid di-tert-butyl ester
O=C(O)C(F)(F)F
trifluoroacetic acid
→
O=C(O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)O
2-(12-phthalimido dodecyl)propane dioic acid
Ausbeute 100.0%

Edukte

CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
5c
CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
2-(12-phthalimido dodecyl)propane dioic acid di-tert-butyl ester
O=C(O)C(F)(F)F
trifluoroacetic acid

Reagenzien

Keine

Lösungsmittel

ClCCl
dichloromethane

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following general procedure D, 16.0 mmol (8.45 g) of 5c and 160 mmol (11.9 mL) of trifluoroacetic acid were reacted in 12 mL of dichloromethane at room temperature and the mixture was processed. Yield 100%.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08501199B2uspto-grants-2013_08