Reaktion #1969509

Reaktionsgleichung

methyl (4-Nitro phenoxy)acetate

Methyl (4-Nitro phenoxy)acetate

→

94

Ausbeute 92.1%

(4-Nitro phenoxy)acetic acid

Ausbeute 92.1%

Lösungsmittel

HCl

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for 8 hours
2. 2
   FiltrationCrude 94 was filtered
3. 3
   Sonstigedried
4. 4
   Sonstigerecrystallized from a mixture of Ethyl acetate:Hexane (1:5)

Vorschrift

A mixture of methyl (4-Nitro phenoxy)acetate 93 (100 grams, 474 mmol) and concentrated HCl (1000 mL) was refluxed for 8 hours. The reaction mass was cooled to room temperature. Crude 94 was filtered, dried, and recrystallized from a mixture of Ethyl acetate:Hexane (1:5) to give pure 94 (86 grams, 92.1%) as a white shining powder. M.p: 186-188.5° C.

Quelle