Reaktion #1966604

Reaktionsgleichung

(1-methyl-1H-indol-3-yl)-oxo-acetic acid

C,C-diphenyl-methylamine

→

N-Benzhydryl-2-(1-methyl-1H-indol-3-yl)-2-oxo-acetamide

Lösungsmittel

CH3CN

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeYield (11%)

Vorschrift

N-Benzhydryl-2-(1-methyl-1H-indol-3-yl)-2-oxo-acetamide was synthesized following scheme II above starting from (1-methyl-1H-indol-3-yl)-oxo-acetic acid and C,C-diphenyl-methylamine. Yield (11%). HPLC ret. time 3.79 min, 10-99% CH3CN, 5 min run; 1H NMR (400 MHz, DMSO-d6) δ 9.56 (d, J=9.1 Hz, 1H), 8.65 (s, 1H), 8.24 (m, 1H), 7.61 (m, 1H), 7.43-7.26 (m, 12H), 6.32 (d, J=9.1 Hz, 1H), 3.90 (s, 3H); ESI-MS 369.1 m/z (MH+).

Quelle