Reaktion #1952271

Reaktionsgleichung

4-cyano-5-ethyl-1-methyl-3-(4-trifluoromethanesulfonyloxyphenyl)—1H-pyrrole-2-carboxylic acid ethyl ester

4-cyano-5-ethyl-1-methyl-3-(4-trifluoromethanesulfonyloxyphenyl)-1H-pyrrole-2-carboxylic acid ethyl ester

4-bromo-benzo(b)thiophene

→

title compound

3-(4-Benzo(b)thiophene-4-yl-phenyl)-4-cyano-1-methyl-1H-pyrrole-2-carboxylic acid ethyl ester

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigePurify the material by silica gel chromatography (Chromatotron™)
2. 2
   Wascheneluting with methylene chloride

Vorschrift

Prepare the title compound in the manner analogous to the procedure set fourth in example E-222 using 4-cyano-5-ethyl-1-methyl-3-(4-trifluoromethanesulfonyloxyphenyl)—1H-pyrrole-2-carboxylic acid ethyl ester (prepared in example E-97a or 97b) and 4-bromo-benzo(b)thiophene. Purify the material by silica gel chromatography (Chromatotron™) eluting with methylene chloride to provide the title compound a white solid. Mass spectrum (m/e): 415.2 (M*+1).

Quelle