Reaktion #1951061

ord-d6ab8da0d96644f58c5c221ad668b4f2

Reaktionsgleichung

C[Si](C)(C)Br
Bromotrimethylsilane
CC(C)OP(=O)(CC1CC1)OC(C)C
cyclopropylmethyl-phosphonic acid diisopropyl ester
→
C[Si](C)(C)OP(=O)(CC1CC1)O[Si](C)(C)C
cyclopropylmethyl-phosphonic acid bis(trimethylsilyl) ester

Edukte

C[Si](C)(C)Br
Bromotrimethylsilane
CC(C)OP(=O)(CC1CC1)OC(C)C
cyclopropylmethyl-phosphonic acid diisopropyl ester

Reagenzien

Keine

Reaktionsbedingungen

Temperatur
5°CELSIUS
Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Temperaturto warm to ambient temperature
  2. 2
    workup.STIRRINGstirred for three hours
  3. 3
    Einengenconcentrated by rotary evaporation

Vorschrift

Bromotrimethylsilane (43 mL, 0.326 mol) was added dropwise to cyclopropylmethyl-phosphonic acid diisopropyl ester (18.00 g, 81.8 mmol) stirred in a reaction flask chilled to 5° C. The resulting solution was allowed to warm to ambient temperature, stirred for three hours, and then concentrated by rotary evaporation yielding crude cyclopropylmethyl-phosphonic acid bis(trimethylsilyl) ester which was used without further purification.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07625880B2uspto-grants-2009_12