Reaktion #1949690

Reaktionsgleichung

Chloracetonitrile

potassium carbonate

product

3-Benzyl-5,7-dihydroxy-4-methyl-2H-1-benzopyran-2-one

DMF

→

3-Benzyl-5,7-bis(cyanomethoxy)-4-methyl-2H-1-benzopyran-2-one

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe reaction mixture was cooled
2. 2
   FiltrationThe solids were filtered
3. 3
   Waschenwashed with water

Vorschrift

Chloracetonitrile (6.86 g), potassium carbonate (23.9 g) and 12.2 g of the product from example 1 a were stirred in 120 ml of DMF at 100° C. under nitrogen for two hours. The reaction mixture was cooled and poured into ice water. The solids were filtered and washed with water. Yield 13.8 g (88%). Melting point 147-154° C.

Quelle