Reaktion #1948156

ord-3920ade4438a4719912fe7045433941c

Reaktionsgleichung

CCCCn1c(=O)c2[nH]c(Br)nc2n(CCCC)c1=O
1,3-di-n-butyl-8-bromo xanthine
C1CCNC1
pyrrolidine
CCCCn1c(=O)c2[nH]c(N3CCCC3)nc2n(CCCC)c1=O
title product
CCCCn1c(=O)c2[nH]c(N3CCCC3)nc2n(CCCC)c1=O
1,3-Di-n-butyl-8-pyrrolidinyl xanthine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 1,3-di-n-butyl-8-bromo xanthine (1 g, 0.0029 ml) and pyrrolidine (0.041 g, 0.0057 mol) using an analogous procedure to that described in Example 19. The title product was obtained as a crystalline solid, m.pt >250 C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06531600B1uspto-grants-2003_03