Reaktion #1944103

Reaktionsgleichung

6-hydroxy-2H-benzofuran-3-one

3-methyl-4-methoxybenzaldehyde

hydrochloric acid

→

desired compound

Ausbeute 39.9%

2-[(3-methyl-4-methoxyphenyl)methylene]-6-hydroxy-3(2H)-benzofuranone

Ausbeute 39.9%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture was refluxed for 1.5 hours
2. 2
   Sonstigeprecipitated crystals
3. 3
   Filtrationwere filtered
4. 4
   Trocknendried over phosphorous pentoxide at a temperature of 60° C. for four hours under reduced pressure

Vorschrift

After 6-hydroxy-2H-benzofuran-3-one 1 g and 3-methyl-4-methoxybenzaldehyde 1.11 g were dissolved in methanol 75 ml, concentrated hydrochloric acid 50 ml was added, and the mixture was refluxed for 1.5 hours. The solution was cooled to room temperature, and precipitated crystals were filtered and dried over phosphorous pentoxide at a temperature of 60° C. for four hours under reduced pressure to obtain the desired compound 0.75 g.

Quelle