Reaktion #1938442

Reaktionsgleichung

4-(6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde

6-fluoro-2-piperidine-4-yl-1H-benzimidazole hydrochloride salt

→

desired compound

Ausbeute 65.7%

7-{4-[4-(6-fluoro-1H-benzimidazol-2-yl)-piperidin-1-ylmethyl]-phenyl}-6-phenylimidazo[1,2-a]pyrimidine

Ausbeute 65.7%

Reaktionsbedingungen

Vorschrift

150 mg (0.5 mmol) 4-(6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde were reacted with 132 mg (0.6 mmol) 6-fluoro-2-piperidine-4-yl-1H-benzimidazole hydrochloride salt in analogy as described in example 6.0. The desired compound (165 mg) was obtained after purification on silicagel.

Quelle