Reaktion #1929054

ord-9e82479849424fd6ac2d50e6fd3911e4

Reaktionsgleichung

COC(=O)CCCCCCCCCCCCCCCBr
16-bromohexadecanoic acid methyl ester
[N-]=[N+]=[N-].[Na+]
sodium azide
→
COC(=O)CCCCCCCCCCCCCCCN=[N+]=[N-]
azide
COC(=O)CCCCCCCCCCCCCCCN=[N+]=[N-]
16-azidohexadecanoic Acid Methyl Ester

Edukte

COC(=O)CCCCCCCCCCCCCCCBr
16-bromohexadecanoic acid methyl ester
[N-]=[N+]=[N-].[Na+]
sodium azide

Reagenzien

Keine

Lösungsmittel

CC#N
acetonitrile

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Temperaturat reflux temperature

Vorschrift

16-bromohexadecanoic acid methyl ester is reacted with sodium azide in acetonitrile for four days at reflux temperature to give the corresponding azide (Zinic et al., Positionally Isomeric Organic Gelators: Structure-Gelation Study, Racemic versus Enantiomeric Gelators, and Solvation Effects, Chem. Eur. J. 2010; 16:3066-82).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08945897B2uspto-grants-2015_02