Reaktion #1929009

Reaktionsgleichung

indole

sodium bisulfite

→

sodium indole-2-sulfonate

Ausbeute 91.0%

Lösungsmittel

ethanol

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe solid precipitate was filtered
2. 2
   Waschenwashed with ether
3. 3
   Sonstigedried

Vorschrift

A solution of 5 g indole in 10 mL ethanol was added to a solution of 8.8 g sodium bisulfite in 30 mL water. The mixture was stirred at room temperature for 12 hrs. The solid precipitate was filtered, washed with ether, and dried to yield sodium indole-2-sulfonate (7.8 g, 91%) as a white solid. The product was used in the next step without further purification. MP>320° C.; IR (KBr, cm−1) 3470, 3250, 1650, 1600, 1490, 1460, 1210, 1170, 1040, 760, 750.

Quelle