Reaktion #1928064

Reaktionsgleichung

Compound 8d

4-[3-(1-Nonyl-4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-yl)-3-oxo-propenyl]-benzoic acid

6-[3-(4-bromophenyl)-acryloyl]-4,4-dimethyl-1-methyl-3,4-dihydro-1H-quinolin-2-one

Intermediate 7f

6-[3-(4-bromophenyl)-acryloyl]-4,4-dimethyl-1-methyl-3,4-dihydro-1H-quinolin-2-one

→

title compound

Ausbeute 20.0%

4-[3-(1-Methyl-4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-yl)-3-oxo-propenyl]-benzoic acid

Ausbeute 20.0%

Reaktionsbedingungen

Vorschrift

Following a procedure similar to that used for the preparation of Compound 8d but using 6-[3-(4-bromophenyl)-acryloyl]-4,4-dimethyl-1-methyl-3,4-dihydro-1H-quinolin-2-one (Intermediate 7f) as the starting material afforded the title compound as a light yellow solid (20% yield).

Quelle